Mulitimin 90 Immunity
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Prescribing Information
Safety Sheet
IMPORTANT SAFETY INFORMATION FOR MULTIMIN® 90: Not for use in humans, keep out of reach of children. Multimin 90 has a preslaughter withdrawal time of 14 days after injection. Do not use during the first trimester of pregnancy or in pre-ruminant calves as safety has not been established. Selenium and copper are toxic if administered in excess and may lead to sudden death, depression, weakness, ataxia, salivation, and drooling. Do not use concurrently with other selenium or copper injections or boluses. Maximum volume per injection site is 7 mL. Allow a minimum of 30 days before considering repeat dosing. See prescribing information.

Your Best Shot at Strategic Trace Mineral Supplementation


Supports immunity

Multimin® 90 (zinc, copper, manganese, and selenium injection) is a proven, one-of-a-kind solution to provide trace minerals. The trace minerals provided by Multimin 90 injection enhance cattle vaccine protection and immune response when used as part of a vaccine protocol. Studies demonstrated that the trace minerals found in every injection of Multimin 90 tended to support higher antibody titers and improved immune response,1 greater BRD protection2 and better vaccine ROI.1
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Antibody titers increased

Administering a vaccine doesn’t guarantee protection. Each animal’s immune system is required to mount a response to the vaccination. The four trace minerals in Multimin 90 support the immune functions necessary for cattle to mount an effective immune response to vaccines.
Research shows that supplementing trace minerals with Multimin 90 resulted in higher BVDV1 antibody titers on day 28, following a booster. This higher response tended to be associated with 80% of calves reaching antibody levels considered protective, versus 53% of the control group.
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Aids in BRD protection

BRD causes an estimated $800 million to $900 million annually in economic losses from death, reduced feed efficiency, and treatment costs.3 Cattle that do recover after treatment will still contribute to economic losses due to lower performance.

A university study1 demonstrated that trace mineral supplementation as part of a vaccination protocol tended to result in increased antibody titer response and enhanced cell mediated and humoral immune response to vaccines. Greater vaccination success should lead to improved protection against BRD and reduced treatments.

Better vaccine ROI

University research results1 showed cattle given supplementation of trace minerals by Multimin 90 injection, at the same time as vaccines, had stronger immune response and tended to have a greater percentage of the herd responding to the vaccine, as measured by antibody titer levels. More cattle responding to vaccinations means better ROI from your vaccines.

Most producers, however, do not measure antibody levels to determine vaccine success. A separate study2 challenged calves with BVDV-2 and IBR to induce illness. The endoscopic images in the video below were captured to compare the clinical effects of the challenged calves following intranasal and booster vaccine with and without trace mineral supplementation by Multimin 90 injection. The video below shows footage of the airways of challenged calves with and without Multimin 90 treatment.

Trace mineral supplementation with Multimin 90 has been researched with these vaccine classes:

Killed vaccines4
Intra-nasal vaccines2
Modified live respiratory1,5
Attenuated-live bacterins5,6
Inactivated multivalent scour vaccines7
Testimonials
"After using the product, we noticed we had very few calves that required immediate action or treatment after arrival. Based on anecdotal observations, I would say we reduced our treatment percentage from 5% to 1% after a few years of strategic trace mineral supplementation with Multimin 90 at processing time."

- Bob Welch
WELCH BROTHERS CATTLE

"Multimin is on top of our list…it has probably had the most dramatic effect on what we do in those protocols as anything we have done over the years."

- Dr. L.D. Barker and sons, Dr. Matt Barker and Dr. Mark Barker

References
1Palomares, R.A., et. al. 2016. Vet. Immunol. Immunopathol. 178(1):88-98.
2Hoyo-Jaramillo, A. et al. 2022. Res Vet Sci. 152:582-595.
3Chirase, N.K., et al. 2001. Anim. Feed Sci. Technol. 93(3):217-228.
4Arthington, J.D., et al. 2014. J. Anim. Sci. 92:2630–2640.
5Bittar J.H.J., et al. 2018. Research in Veterinary Science. 119:250-258.
6Bittar J.H.J., et al. 2017. The Professional Animal Scientist 34:59-66.
7Palomares, R.A., et al. 2021. 102nd Conference of Research Workings in Animal Diseases. Chicago, IL. 433.


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